DIM is a metabolite of indole-3-carbinol (from broccoli, cauliflower). Shifts estrogen metabolism toward 2-hydroxyestrone (favorable) and away from 16α-hydroxyestrone (less favorable). Used for estrogen-dominance symptoms in women and aromatase support in men.
Dose: 100-200mg daily.
Caveats: Can lower estradiol too much in some men; monitor labs. Not for pregnancy.