Nicotinamide Adenine Dinucleotide.
NAD+ is a coenzyme present in every cell of the body. It is essential for mitochondrial function, DNA repair, and the regulation of cellular aging via the sirtuin and PARP pathways. Levels decline measurably with age.
Use
Mitochondrial support. Energy metabolism. Anti-aging protocols. Cognitive performance. Recovery from physical and metabolic stress.
Route
Intravenous infusion for therapeutic dosing. Oral precursors (NMN, NR) for daily support. Subcutaneous and intranasal forms exist but are less common clinically.
Pairs with
MOTS-c for mitochondrial biogenesis. Methylene blue for cognitive applications. Glutathione infusion stack.
Status
FDA-approved as a supplement. Clinical IV protocols are off-label.