Melanocortin receptor agonist. Bremelanotide.

CNS-mediated arousal pathway, distinct from vascular agents like sildenafil.

Use

Hypoactive sexual desire, both sexes.

Route

Subcutaneous injection or intranasal, as needed.

Pairs with

Sleep, stress, hormone optimization. Hormone replacement where indicated.

Status

FDA-approved for premenopausal women (Vyleesi). Off-label for men.